COMPOSITION FOR PREVENTING OR TREATING LIVER DISEASES COMPRISING SONICATED GINSENG BERRY

• Main Authors: KIM, SUNG TAE, BAE, JIN HYUNG, NAM, YOON JIN, SOHN, UY DONG, KO, SUNG KWON
• Format: Patent
• Language: English; Korean
• Published: 12.04.2016
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention relates to a composition for preventing or treating liver diseases comprising ultrasonicated ginseng fruit extract as an active ingredient. More particularly, it has been found that ginseng fruit extract having an increased amount of main pharmacological ingredients, ginsenosides Rg2, Rh1 and F4 through ultrasonication shows a liver-protecting effect similar to or higher than the effect of silymarin used currently as an agent for treating liver diseases. Therefore, the composition comprising ultrasonicated ginseng fruit extract as an active ingredient according to the present invention can be provided as a pharmaceutical composition for preventing or treating liver diseases, such as liver failure, non-alcoholic fatty liver disease (NAFLD) or alcoholic fatty liver disease (AFLD), or a health-aid food composition. 본 발명은 초음파 처리된 인삼열매 추출물을 유효성분으로 함유하는 간질환 예방 또는 치료용 조성물에 관한 것으로, 보다 상세하게는 초음파 처리를 통하여 인삼의 주요 약리성분인 진세노사이드(ginsenoside) Rg2, Rh1 및 F4 함량이 증가된 인삼열매 추출물이 간질환 치료제로 사용되고 있는 실리마린과 유사하거나, 탁월한 간 보호 효과를 나타내는 것을 확인하였다. 따라서, 본 발명의 초음파 처리된 인삼열매 추출물을 유효성분으로 함유하는 조성물은 간부전 및 비 알콜성 지방간(Non-Alcoholic Fatty Liver Disease ; NAFLD) 또는 알콜성 지방간(Non-Alcoholic Fatty Liver Disease ; NAFLD)과 같은 간질환 예방 또는 치료를 위한 약학조성물 또는 건강식품조성물로 제공될 수 있다.