HETEROBICYCLOARYL RORC2 INHIBITORS AND METHODS OF USE THEREOF

본 발명은 화합물, 약학적 조성물, RORγ 활성의 억제 방법 및/또는 개체에서 IL-17의 양의 감소 방법, 및 이러한 화합물 및 약학적 조성물을 사용하는 다양한 의학적 장애의 치료 방법을 제공한다. The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating variou...

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Main Authors KIEFER JAMES RICHARD JR, MEYERS MARVIN JAY, ZAMARATSKI EDOUARD, ZAPF CHRISTOPH WOLFGANG, JONES PETER, THORARENSEN ATLI, WENNERSTAL GORAN MATTIAS, KURUMBAIL RAVI G, FLICK ANDREW CHRISTOPHER, MENTE SCOT RICHARD, KAILA NEELU, SCHNUTE MARK EDWARD, BLINN JAMES ROBERT, XING LI
Format Patent
LanguageEnglish
Korean
Published 06.04.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:본 발명은 화합물, 약학적 조성물, RORγ 활성의 억제 방법 및/또는 개체에서 IL-17의 양의 감소 방법, 및 이러한 화합물 및 약학적 조성물을 사용하는 다양한 의학적 장애의 치료 방법을 제공한다. The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.
Bibliography:Application Number: KR20167005139