NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF DISEASE CAUSED BY INFLUENZA VIRUS INFECTION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

• Main Authors: RAGHAVENDRA ACHARY, KIM, MEE HYEIN, JUNG, YOUNG SIK, LEE, CHONG KYO, KIM, PIL HO, HAN, SOO BONG, SHIN, JIN SOO
• Format: Patent
• Language: English; Korean
• Published: 24.02.2016
• Subjects: ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES; CANDLES; CHEMISTRY; DETERGENT COMPOSITIONS; DETERGENTS; FATTY ACIDS THEREFROM; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY; RECOVERY OF GLYCEROL; RESIN SOAPS; SOAP OR SOAP-MAKING; USE OF SINGLE SUBSTANCES AS DETERGENTS

The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active component for preventing or treating diseases related with influenza virus infection. The novel compound represented by chemical formula 1 has remarkable antivirus activity against influenza virus without cytotoxicity to human cells and thus has little side effects to human bodies. Therefore, the pharmaceutical composition having the same as an active component can be usefully used for preventing or treating diseases which occur through influenza virus infection such as flu, cold, sore throat, bronchitis, pneumonia, avian influenza, swine flu, goat flu, etc. 본 발명은 신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물에 관한 것이다. 본 발명에 따른 화학식 1로 표시되는 신규한 화합물은 인플루엔자 바이러스에 대한 항바이러스 활성이 현저히 우수할 뿐만 아니라, 인간 세포에 대한 세포독성이 없어 인체에 부작용이 적으므로, 이를 유효성분으로 함유하는 약학적 조성물은 인플루엔자 바이러스 감염에 의해 발병되는 독감, 감기, 인후염, 기관지염, 폐렴, 조류독감, 돼지독감, 염소독감 등의 예방 또는 치료용 유용하게 사용될 수 있다.