LEVOISOVALERYLSPIRAMYCIN II OR III, PREPARATIONS, PREPARATION METHODS AND USES THEREOF

• Main Authors: HAO YUYOU, JIANG YANG
• Format: Patent
• Language: English; Korean
• Published: 15.02.2016
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DERIVATIVES THEREOF; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; SUGARS; VINEGAR; WINE

레보이소발레릴스피라마이신 I, II 또는 III, 이의 제제, 제조 방법 및 용도가 개시된다. 제제는 레보이소발레릴스피라마이신 I, II 또는 III과 약제학적 허용성 담체 및/또는 보강제를 함유하며, 레보이소발레릴스피라마이신 I, II 또는 III의 순도는 90wt% 이상이다. 상기 레보이소발레릴스피라마이신 I, II 또는 III은 항균 활성이 양호하고 그 제제는 주사용 용액, 주사용 분말 또는 동결건조 분말을 포함한다. Disclosed are crystalline levoisovalerylspiramycin II and corresponding preparations, preparing methods and uses thereof. The preparations comprise crystalline levoisovalerylspiramycin II and pharmaceutically acceptable carrier and/or adjuvant, wherein the purity of levoisovalerylspiramycin II is above 90 wt%. The crystalline levoisovalerylspiramycin II has a good antibacterial activity, and the preparations include solution for injection, powder for injection or lyophilized powder for injection.