RELEASE OF BIOLOGICALLY ACTIVE AGENTS FROM POLYMERIC COMPOSITE PARTICLES

• Main Authors: CARUSO DAILEY MARY M, HEINZEN LUKE E, SAHOUANI HASSAN, EL HEDOK IBRAHIM A
• Format: Patent
• Language: English; Korean
• Published: 27.01.2016
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; COMPOSITIONS BASED THEREON; FISHING; FORESTRY; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; THEIR PREPARATION OR CHEMICAL WORKING-UP; TRAPPING; WORKING-UP

다양한 생물 활성제의 저장 및 전달에 사용될 수 있는 중합체 복합 입자가 제공된다. 중합체 복합 입자는 다공성 중합체 코어 및 다공성 중합체 코어 주위의 코팅 층을 함유한다. 다공성 중합체 복합 입자는 전형적으로, 다공성 중합체 코어 내에 위치되어 있지만 다공성 중합체 코어에 공유 결합되지 않은 생물 활성제를 추가로 포함한다. 생물 활성제는 다공성 중합체 코어로부터 코팅 층을 통해 확산됨으로써 중합체 복합 입자로부터 방출될 수 있다. Polymeric composite particles are provided that can be used for the storage and delivery of various biologically active agent. The polymeric composite particles contain a porous polymeric core and a coating layer around the porous polymeric core. The porous polymeric composite particles typically further include a biologically active agent positioned within the porous polymeric core but not covalently bonded to the porous polymeric core. The biologically active agent can be released from the polymeric composite particle by diffusing out of the porous polymeric core through the coating layer.