INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO)

• Main Authors: SEITZ STEVEN P, CHEN BIN, BALOG JAMES AARON, HART AMY C, MARKWALDER JAY A, HUANG AUDRIS, CHEN LIBING
• Format: Patent
• Language: English; Korean
• Published: 18.11.2015
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

인돌아민 2,3-디옥시게나제 (IDO)의 효소적 활성을 조절 또는 억제하는 화합물, 상기 화합물을 포함하는 제약 조성물 및 본 발명의 화합물을 이용하여 증식성 장애, 예컨대 암, 바이러스 감염 및/또는 염증성 장애를 치료하는 방법이 개시된다. There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.