AGENTS FOR TREATING GENETIC DISEASES RESULTING FROM NONSENSE MUTATIONS, AND METHODS FOR IDENTIFYING THE SAME

Disclosed is treatment of genetic neurodegenerative or neurodevelopmental diseases that are caused by or associated with nonsense mutations or premature termination codons using macrolides. Further disclosed are methods for identifying agents that induce read-through of nonsense mutations and premat...

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Bibliographic Details
Main Authors MEGIDDO DALIA, ROSIN ARBESFELD RINA, CASPI MICHAL
Format Patent
LanguageEnglish
Korean
Published 28.08.2015
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Disclosed is treatment of genetic neurodegenerative or neurodevelopmental diseases that are caused by or associated with nonsense mutations or premature termination codons using macrolides. Further disclosed are methods for identifying agents that induce read-through of nonsense mutations and premature termination codons and uses thereof.
Bibliography:Application Number: KR20157020037