INHIBITORS OF BRUTON'S TYROSINE KINASE

• Main Authors: LOPEZ TAPIA FRANCISCO JAVIER, LAINE DRAMANE IBRAHIM, STEVENSON CHRISTOPHER, IYER RAMAN MAHADEVAN, PHILLIPS JONATHAN E
• Format: Patent
• Language: English; Korean
• Published: 02.07.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

본 발명은 본원에 기술된 바와 같은 Btk 억제제 화합물 6-tert-부틸-8-플루오로-2-{3-하이드록시메틸-4-[1-메틸-5-(1'-메틸-1',2',3',4',5',6'-헥사하이드로-[3,4']바이피리딘일-6-일아미노)-6-옥소-1,6-다이하이드로-피리다진-3-일]-피리딘-2-일}-2H-프탈라진-1-온, 2-(2-{3-[5-(5-아제티딘-1-일메틸-1-메틸-1H-피라졸-3-일아미노)-1-메틸-6-옥소-1,6-다이하이드로-피리다진-3-일]-2-하이드록시메틸-페...