DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, ONCOLOGICAL DISEASES AND RELATED DISORDERS

• Main Authors: CHERUKU SRINIVASA R, LEE JOHN W, GLADDING JEFFERY A, THOTA SAMBAIAH, NGUYEN DIEU, LOEBELENZ JEAN R, NORMAN JAMES J, ROSENFELD CRAIG, WARNER JOHN C
• Format: Patent
• Language: English; Korean
• Published: 03.06.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

일 실시예에 있어서, 본 발명은 2-아자, 2-옥사 및 2-티아-2,3-디히드로-6-아자페날렌 화합물 및 조성물, 및 본 명세서에 개시된 바와 같이 상기 화합물 및 조성물을 사용하여 신경 질환 치료를 필요로 하는 환자의 신경 질환을 치료하는 방법에 관한 것이다. In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.