SINGLE-STRANDED NUCLEIC ACID APTAMERS SPECIFICALLY BINDING TO KLEBSIELLA PNEUMONIAE AND METHOD FOR DETECTING K. PNEUMONIAE USING THE SAME

• Main Authors: KIM, BYOUNG CHAN, KIM, YEON SEOK, SONG, MIN YOUNG, CHUNG, JIN YANG, JURNG, JONG SOO
• Format: Patent
• Language: English; Korean
• Published: 28.05.2015
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

The present invention relates to a single-stranded nucleic acid aptamer specifically bound to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae using the same. The aptamer, the method using the same, a composition, a kit, or a sensor of the present invention not only enables a user to specifically detect Klebsiella pneumoniae existing in a sample for testing water quality, food, a biomaterial for medical purposes but also can be applied to fields such as food hygiene and medical diagnosis. 본 발명은 클렙시엘라 뉴모니아에 특이적으로 결합하는 단일가닥 핵산 앱타머 및 이를 이용한 클렙시엘라 뉴모니아의 검출방법에 관한 것이다. 본 발명의 앱타머 및 이를 이용한 방법, 조성물, 키트 또는 센서는 수질, 식품, 의료 샘플에 존재하는클렙시엘라 뉴모니아를 특이적으로 검출할 수 있을 뿐 아니라 식품 위생이나 의료 진단 등의 분야에도 활용될 수 있다.