A kit and a method for simultaneously detecting HLA-B＊5801 and HLA-B＊5701 alleles

The present invention relates to a method for simultaneously detecting HLA-B*5801 allele and HLA-B*5701 allele which are for predicting adverse drug reactions of allopurinol and abacavir, and to a kit thereof and, more specifically, to a method and a kit for simultaneously detecting HLA-B*5801 allel...

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Main Authors HAN, SUNG HEE, KIM, YUN TAE, LEE, KYOUNG RYUL, RYU, JAE SONG, LEE, SANG HOO, KIM, YOUNG JIN, KIM, YONG WOO
Format Patent
LanguageEnglish
Korean
Published 19.03.2015
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a method for simultaneously detecting HLA-B*5801 allele and HLA-B*5701 allele which are for predicting adverse drug reactions of allopurinol and abacavir, and to a kit thereof and, more specifically, to a method and a kit for simultaneously detecting HLA-B*5801 allele and HLA-B*5701 allele using reverse primer capable of specifically and simultaneously amplifying the HLA-B*5801 allele and HLA-B*5701 allele among various HLA-B alleles and forward primer capable of amplifying including regions showing sequence difference among the alleles.
Bibliography:Application Number: KR20130108134