NOVEL PROCESS FOR PREPARATION OF 4-(4-AMINOPHENYL)-3-MORPHOLINONE

The present invention relates to a method for producing 4-(4-aminophenyl)-3-morpholinone comprising a step for deoxidizing by reacting sodium hydrosulfite (Na2S2O4) with 4-(4-nitrophenyl)-3-morpholinone. The method for producing 4-(4-aminophenyl)-3-morpholinone in the present invention is safe and e...

Full description

Saved in:
Bibliographic Details
Main Authors YOO, CHOONG LEOL, PARK, DAE JONG, KIM, HYUNG SANG
Format Patent
LanguageEnglish
Korean
Published 04.11.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to a method for producing 4-(4-aminophenyl)-3-morpholinone comprising a step for deoxidizing by reacting sodium hydrosulfite (Na2S2O4) with 4-(4-nitrophenyl)-3-morpholinone. The method for producing 4-(4-aminophenyl)-3-morpholinone in the present invention is safe and economical by not using high temperature and high pressure hydrogen gas, is cheaper than a hydrogenation catalyst thus facilitating mass production, and is also capable of crystallizing after finishing a reaction in water, thus being eco-friendly. A structure of the 4-(4-aminophenyl)-3-morpholinone is represented by the following chemical formula (I).
Bibliography:Application Number: KR20130046259