TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF KV1.3 POTASSIUM CHANNELS

Activation of brown adipose tissue, treatment of obesity and/or treatment of obesity-related disorders in human or non-human animal subjects by administering to the subject a potassium channel inhibiting agent. The potassium channel inhibiting agent may comprise ShK toxin or a modified ShK toxin. Ex...

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Main Authors CORSI PAOLO SASSONE, MAHAN KRISTIN LYNN ECKEL, IADONATO SHAWN, MIRBOLOOKI REZA M, UPADHAYAY SANJEEV KUMAR, MUKERGEE JOSEPH, CHANDY GEORGE K, WANG PING H
Format Patent
LanguageEnglish
Korean
Published 11.09.2014
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Activation of brown adipose tissue, treatment of obesity and/or treatment of obesity-related disorders in human or non-human animal subjects by administering to the subject a potassium channel inhibiting agent. The potassium channel inhibiting agent may comprise ShK toxin or a modified ShK toxin. Examples of modified ShK toxins include ShK-186.
Bibliography:Application Number: KR20147012093