PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF

The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound o...

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Bibliographic Details
Main Authors SZELIGA JAN, FABIAN STEVEN R, SHAH SYED M, BAZHINA NATALIYA, DONATO GEORGE JOSEPH, OFSLAGER CHRISTIAN, LOKHNAUTH JOHN, MEGATI SREENIVASULU, RADEBAUGH GALEN, MELUCCI CHARLES, ZHANG HUYI, PATEL NIKETA, ZHU TIANMIN
Format Patent
LanguageEnglish
Korean
Published 18.07.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a use of a prefilled syringe comprising a liquid composition comprising N-methylnaltrexone bromide and that is substantially free from tungsten, for storing the N-methylnaltrexone, thus protecting the N-methylnaltrexone against degradation during storageto a compound of formula II-1:
Bibliography:Application Number: KR20147017013