4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof, a method for preparing the same and a pharmaceutical composition comprising the same. The 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof may effectively in...

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Bibliographic Details
Main Authors TAK, HEE JAE, LEE, GYU JIN, SHIN, SEUNG YUB, LEE, CHUN HO, PARK, CHAN SUN, KIM, YOUNG HWAN, LEE, HO JIN
Format Patent
LanguageEnglish
Korean
Published 07.05.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof, a method for preparing the same and a pharmaceutical composition comprising the same. The 4,5-dihydro-1H-pyrazole derivative or pharmaceutically acceptable salts thereof may effectively increase LXR transcriptional activity, and therefore, can be usefully applied to the prevention and treatment of cholesterol metabolism disorders including cholesterol gallstones, hyperlipidemia, coronary sclerosis and atherosclerosis.
Bibliography:Application Number: KR20120119077