TRANSDERMAL ADHESIVE COMPOSITIONS, DEVICES, AND METHODS

The present invention relates to a transdermal drug delivery device comprising:a transdermal adhesive composition comprising:an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; andat least one pharmaceutically active compound which is s...

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Bibliographic Details
Main Authors DIZIO JAMES P, JOHNSON ELIZABETH E, WU ZHENG ZHI, PRESZLER PRINCE AMY
Format Patent
LanguageEnglish
Korean
Published 30.12.2013
Subjects
ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE
ADHESIVES
CHEMISTRY
DYES
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
NATURAL RESINS
NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL
PAINTS
POLISHES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
USE OF MATERIALS AS ADHESIVES
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Summary:The present invention relates to a transdermal drug delivery device comprising:a transdermal adhesive composition comprising:an adhesive comprising a washed polymerization reaction product of at least two ethylenically unsaturated monomers; andat least one pharmaceutically active compound which is susceptible to oxidative degradation; wherein the at least two ethylenically unsaturated monomers, if present in the adhesive as unreacted monomers, are present at a level of less than 200 ppm of total unreacted monomer, based upon the total weight of the adhesive;a backing sheet coated with the transdermal adhesive composition, wherein the transdermal adhesive composition coating covers at least a portion of a major surface of the backing sheet wherein any free radical initiator, if present in the adhesive, is present at a level of less than 20 ppm, based upon the total weight of the adhesive; andwherein less than 0.1% of antioxidant is present in the transdermal adhesive composition.
Bibliography:Application Number: KR20137004235