ANTIBODY-DRUG CONJUGATE FORMED THROUGH TRANSGLUTAMINASE AND USE THEREOF
The present invention relates to a method of producing an antibody-medicine corporate body comprising a step of making mutated antibody including glutamine and medicine including free amine group react under the existence of transglutaminase, to an antibody-medicine corporate body produced thereby,...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English Korean |
| Published |
04.12.2013
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to a method of producing an antibody-medicine corporate body comprising a step of making mutated antibody including glutamine and medicine including free amine group react under the existence of transglutaminase, to an antibody-medicine corporate body produced thereby, to an antibody-medicine corporate body in which medicine including mutated antibody and free amine group connected by isopeptide bond, to a composition for treating cancer including the antibody-medicine corporate body, to a method for treating cancer by using the antibody-medicine corporate body, and to a mutated body to which peptide including glutamine and antibody are connected. |
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| AbstractList | The present invention relates to a method of producing an antibody-medicine corporate body comprising a step of making mutated antibody including glutamine and medicine including free amine group react under the existence of transglutaminase, to an antibody-medicine corporate body produced thereby, to an antibody-medicine corporate body in which medicine including mutated antibody and free amine group connected by isopeptide bond, to a composition for treating cancer including the antibody-medicine corporate body, to a method for treating cancer by using the antibody-medicine corporate body, and to a mutated body to which peptide including glutamine and antibody are connected. |
| Author | MOON, KYUNG DUK PARK, SANG KYUNG SONG, DAE HAE KIM, YOUNG MIN KO, MIN JI |
| Author_xml | – fullname: MOON, KYUNG DUK – fullname: KO, MIN JI – fullname: PARK, SANG KYUNG – fullname: KIM, YOUNG MIN – fullname: SONG, DAE HAE |
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| RelatedCompanies | HANWHA CHEMICAL CORPORATION |
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| Snippet | The present invention relates to a method of producing an antibody-medicine corporate body comprising a step of making mutated antibody including glutamine and... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | ANTIBODY-DRUG CONJUGATE FORMED THROUGH TRANSGLUTAMINASE AND USE THEREOF |
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