METHOD FOR PREPARATION OF CHIRAL OXINDOLE DERIVATIVES

PURPOSE: A method for preparing chiral oxindole is provided to obtain an optically active material with high optical purity using a chiral catalyst. CONSTITUTION: A method for preparing chiral oxindole comprises a step of reacting 3-alkyl-substituted oxindole with alpha, beta-unsaturated ketone unde...

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Bibliographic Details
Main Authors WOO, SAET BYEOL, LEE, HYUN JOO, KIM, DAE YOUNG, LIM, YEONG JO
Format Patent
LanguageEnglish
Korean
Published 04.06.2013
Subjects
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:PURPOSE: A method for preparing chiral oxindole is provided to obtain an optically active material with high optical purity using a chiral catalyst. CONSTITUTION: A method for preparing chiral oxindole comprises a step of reacting 3-alkyl-substituted oxindole with alpha, beta-unsaturated ketone under the presence of a chiral catalyst. The chiral organic catalyst is used as the chiral catalyst. 3-alkyl-subsituted oxindole has a structure of chemical formula 4. The alpha, beta-unsaturated ketone has a structure of chemical formula 5.
Bibliography:Application Number: KR20110124501