A PROCESS FOR THE PREPARATION OF HIGHLY PURE AMBRISENTAN

The present invention relates to an improved and novel process for the preparation of highly pure (>99.8%) (+)-2(S)-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionic acid (Ambrisentan) of formula (I).

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Bibliographic Details
Main Authors ADIBHATLA KALI SATYA BHUJANGA RAO, KOMPELLA AMALA, KASA SRINIVASU, NANNAPANENI VENKAIAH CHOWDARY, BALINA VEERA SWAMY
Format Patent
LanguageEnglish
Korean
Published 24.05.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to an improved and novel process for the preparation of highly pure (>99.8%) (+)-2(S)-(4,6-dimethylpyrimidin-2-yloxy)-3-methoxy-3,3-diphenylpropionic acid (Ambrisentan) of formula (I).
Bibliography:Application Number: KR20127026731