COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPRISING NAD GLYCOHYDROLASE INHIBITOR AS ACTIVE INGREDIENT

PURPOSE: A composition for prevention and treatment of diabetes including a NAD glycohydrolase inhibitor as an active ingredient is provided to be used as a cure for diabetes, especially type 2 diabetes, by accelerating hypoglycemic and insulin secretion. CONSTITUTION: A composition for prevention a...

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Bibliographic Details
Main Authors PARK, KWANG HYUN, NAM, TAE SIK, KIM, UH HYUN, KIM, BYUNG JU
Format Patent
LanguageEnglish
Korean
Published 02.05.2013
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
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Summary:PURPOSE: A composition for prevention and treatment of diabetes including a NAD glycohydrolase inhibitor as an active ingredient is provided to be used as a cure for diabetes, especially type 2 diabetes, by accelerating hypoglycemic and insulin secretion. CONSTITUTION: A composition for prevention and treatment of diabetes comprises a development inhibitor or an activity inhibitor of NADase as an active ingredient. A NADase is originated from a mammal. The NADase is encoded as a base sequence of sequence number 1 or 2. Diabetes is type 2 diabetes. The active inhibitor is any one selected from a group comprised of antisense nucleotide, siRNA(short interfering RNA), and shRNA(short hairpin RNA) for complementarily uniting to mRNA of a NADase gene.
Bibliography:Application Number: KR20120116718