SYNTHETIC METHOD OF QUERCETIN-3-GLUCOSIDE

PURPOSE: A chemical mass-synthesis method of quercetin-3-glucocide is provided to mass-synthesize by using quercetin or rutin, and beta-D-glucocide as a starting material. CONSTITUTION: A chemical mass-synthesis method of quercetin-3-glucocide comprises the following steps: synthesizing (2S,3S,4R,5S...

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Main Authors LIM, YOONG HO, PARK, HYE RI, CHONG, YOU HOON, KANG, JI HOON
Format Patent
LanguageEnglish
Korean
Published 12.04.2013
Subjects
CHEMISTRY
CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS
DERIVATIVES THEREOF
GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC
GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Summary:PURPOSE: A chemical mass-synthesis method of quercetin-3-glucocide is provided to mass-synthesize by using quercetin or rutin, and beta-D-glucocide as a starting material. CONSTITUTION: A chemical mass-synthesis method of quercetin-3-glucocide comprises the following steps: synthesizing (2S,3S,4R,5S6R)-2-(acetoxymethyl)-6-(2-(3,4-dihydroxy phenyl)-5,7-dihydroxy-4-iodine-4H-chromenyl-3-oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate through region selective glycation by using quercetin and beta-D-glucocide as starting materials; and performing elimination reaction of a protecting group using sodium methoxide.
Bibliography:Application Number: KR20110100572