NANOPARTICLES FORMED BY ENCAPSULATING AN ANTICANCER DRUG INTO GLYCOLCHITOSAN-CHOLANIC ACID COMPLEX AND A PROCESS FOR THE PREPARATION THEREOF
PURPOSE: A nanoparticle having a glycolchitosan-bile acid composite containing a hydrophtic anticancer agent is provided to ensure excellent water solubility and to be used as an injector. CONSTITUTION: A nanoparticle is prepared by sealing a glycolchitosan-bile acid composite containing a hydrophot...
Saved in:
Main Authors | , , , , , , , , , , |
---|---|
Format | Patent |
Language | English Korean |
Published |
26.07.2012
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | PURPOSE: A nanoparticle having a glycolchitosan-bile acid composite containing a hydrophtic anticancer agent is provided to ensure excellent water solubility and to be used as an injector. CONSTITUTION: A nanoparticle is prepared by sealing a glycolchitosan-bile acid composite containing a hydrophotic anticancer agent. The molecular weight of glycolchitosan monomers is 10-20 kDa. The diameter of the particle is 100-200 nm. The hydrophobic anticancer agent is daunoamicin, docetaxel, paclitaxel, cisplatin, mitomycin-C or 5-fluorouracil. An injector contains the nanoparticles. |
---|---|
Bibliography: | Application Number: KR20110004989 |