CATHEPSIN C INHIBITORS

Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.

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Bibliographic Details
Main Authors SOLLIS STEVEN L, EVANS BRIAN, WALL MICHAEL D, PALOVICH MICHAEL R, BULLION ANN M, BUSCH PETERSEN JAKOB, NEVINS NEYSA, LI HUIJIE, ANDERSON NIALL
Format Patent
LanguageEnglish
Korean
Published 13.06.2012
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.
Bibliography:Application Number: KR20127006239