OXIDATION-STABILIZED TAMPER-RESISTANT DOSAGE FORM

The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage f...

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Bibliographic Details
Main Authors SCHWIER SEBASTIAN, BERTRAM ULRIKE, GALIA ERIC, GEISSLER ANJA, GRIESSMANN KORNELIA, BARTHOLOMAEUS JOHANNES, BARNSCHEID LUTZ
Format Patent
LanguageEnglish
Korean
Published 24.04.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and - a polyalkylene oxide (C) having a weight average molecular weight M w of at least 200,000 g/mol.
Bibliography:Application Number: KR20127001863