PHARMACEUTICAL COMPOSITION CONTAINING ANTIDEPRESSANT

PURPOSE: A method for manufacturing a sustained release formulation of antidepressant is provided to obtain a formulation with same drug release pattern with conventional formulations. CONSTITUTION: A sustained release formulation of duloxetine hydrochloride comprises an inactive core, a drug layer...

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Bibliographic Details
Main Authors CHOI, JAE SEUNG, LEE, KYUNG SOO, NAM, KYOUNG TAE
Format Patent
LanguageEnglish
Korean
Published 09.03.2012
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A method for manufacturing a sustained release formulation of antidepressant is provided to obtain a formulation with same drug release pattern with conventional formulations. CONSTITUTION: A sustained release formulation of duloxetine hydrochloride comprises an inactive core, a drug layer containing duloxetin hydrochloride, separation layer, and enteric layer containing cellulose acetate phthalic acid. A method for preparing the sustained release formulation comprises: a step of preparing the inactive core; a step of applying drug liquid on the inactive core to form the drug layer; a step of applying the separation layer coating solution; and a step of applying the enteric coating solution.
Bibliography:Application Number: KR20100074900