NANO PARTICLES FOR TUMOR-TARGETING AND PROCESSES FOR THE PREPARATION THEREOF

PURPOSE: A pharmaceutical composition containing nanoparticles in an aqueous medium is provided to enable active and passive targeting of an anticancer drug. CONSTITUTION: A pharmaceutical composition of nano-dispersion for targeting contains nanoparticles having 10-1,000 nm of average particle size...

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Main Authors MIN, MI HONG, WOO, MIN NA, AHN, BYUNG NAK, KIM, JOO EUN, PARK, SEONG BAE, YANG, JUN MO, CHOI, HYUN HO
Format Patent
LanguageEnglish
Korean
Published 26.05.2011
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A pharmaceutical composition containing nanoparticles in an aqueous medium is provided to enable active and passive targeting of an anticancer drug. CONSTITUTION: A pharmaceutical composition of nano-dispersion for targeting contains nanoparticles having 10-1,000 nm of average particle size in an aqueous medium. The nanoparticle contains therapeutically effective amount of anticancer drug; bivalent or trivalent transition metal ion or alkali earth metal ion; and oil. Hyaluronic acid or salt thereof is conjugated on the surface of the nanoparticles. The aqueous medium is distilled water, injection solution, saline solution, dextrose, or amino acid liquid.
Bibliography:Application Number: KR20090112718