SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[B]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS

• Main Authors: MOODY JEANNE V, ZHU XIUWEN, JONES ROBERT M, ULLMAN BRETT, BUZARD DANIEL J, HAN, SANG DON, LEHMANN JUERG, STIRN SCOTT, KIM, SUN HEE
• Format: Patent
• Language: English; Korean
• Published: 05.04.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically acceptable salts thereof, which exhibit useful pharmacological properties, for example, as agonists of the S1P1 receptor.Also provided by the pr...