TARGETED COAGULATION FACTORS AND METHOD OF USING THE SAME

Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and t...

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Bibliographic Details
Main Authors KIM JI YUN, FELDMAN RICHARD, WU JAMES, JIANG HAIYAN, PAN JUNLIANG, MCLEAN KIRK, ZHAO XIAO YAN, PIERCE GLENN
Format Patent
LanguageEnglish
Korean
Published 07.03.2011
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Targeted coagulation factors comprising a coagulation factor linked with at least one domain that specifically binds to a membrane protein on a blood cell is provided. The disclosed targeted coagulation factors increase the efficiency of coagulation factors and prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.
Bibliography:Application Number: KR20107028245