QUINOLINES AS INHIBITORS OF FARNESYL PYROPHOSPHATE SYNTHASE

The invention relates to a compound of formula (I) wherein the substituents are as described in the specification, which are useful as farnesyl pyrophosphate synthase modulators, e.g. in the treatment of proliferative diseases, to methods of manufacturing such compounds and to intermediates thereof.

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Bibliographic Details
Main Authors OFNER SILVIO, STAUFFER FREDERIC, MARZINZIK ANDREAS, COTESTA SIMONA, AMSTUTZ RENE, BOLD GUIDO, JAHNKE WOLFGANG, MUELLER HARTWIEG CONSTANZE, ZIMMERMANN JOHANN
Format Patent
LanguageEnglish
Korean
Published 29.11.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a compound of formula (I) wherein the substituents are as described in the specification, which are useful as farnesyl pyrophosphate synthase modulators, e.g. in the treatment of proliferative diseases, to methods of manufacturing such compounds and to intermediates thereof.
Bibliography:Application Number: KR20107019046