PYRIMIDINYL-PIPERAZINES USEFUL AS D3/D2 RECEPTOR LIGANDS

The present invention relates to new dopamine Dand Dligands of formula (I): wherein Rl, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes...

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Main Authors BARTANE SZALAI GIZELLA, DOMANY GYORGY, GYERTYAN ISTVAN, SCHMIDT EVA, FARKAS SANDOR, KISS BELA, LASZY JUDIT, KOMLODI ZSOLT, SAGHY KATALIN, AGAINE CSONGOR EVA
Format Patent
LanguageEnglish
Korean
Published 19.07.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to new dopamine Dand Dligands of formula (I): wherein Rl, R2 and Q are as described herein, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates and/or polymorphs thereof. The invention also relates to processes for preparing the same, to compositions containing the same and to their use in the treatment and/or prevention of conditions which requires modulation of dopamine receptors. 본 발명은 화학식(I)의 신규 도파민 D및D리간드 및/또는 그의 기하 이성질체 및/또는 입체이성질체 및/또는 부분입체이성질체 및/또는 염 및/또는 수화물 및/또는 용매화물 및/또는 다형태에 관한 것이다. 본 발명은 또한 그의 제조 방법, 그를 함유하는 조성물 및 도파민 수용체의 조절을 필요로 하는 상태의 치료 및/또는 예방에서 그의 용도에도 관한 것이다.
Bibliography:Application Number: KR20097020486