NOVEL THIAZOLINE-BASED COMPOUNDS AND T-TYPE CALCIUM CHANNEL INHIBITORS CONTAINING THE SAME

PURPOSE: A thiazoline compounds and a T-type calcium channel inhibitor containing the same are provided to treat diseases relating to T-type calcium channel overexpression. CONSTITUTION: A thiazoline compounds have a structure of chemical formula 1. A composition for preventing and treating diseases...

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Main Authors CHOI, KYUNG IL, KIM, YOON JEE, CHUNG, HYE JIN, KIM, KEY SUN, RHIM, HYE WHON, CHO, YONG SEO, ROH, EUN JOO, CHOI, KEE HYUN, BAEK, YI YEON, NAM, KEE DAL, CHOO, HYUN AH, KEUM, GYO CHANG, LEE, CHEOL JU, NAM, GHIL SOO, KIM, YOUNG SOO, SONG, CHI MAN, SHIN, HEE SUP, CHEONG, CHAN SEONG, PARK, WOONG SEO, PAE, AE NIM, HAHN, HOH GYU, KIM, DONG JIN, KIM EUNICE EUN KYEONG, LEE, JAE KYUN, KANG, SOON BANG, MAH, HE DUCK, MIN, SUN JOON, SHIN, DONG YUN, SEO, SEON HEE, SHIN, KYE JUNG, CHUNG, HE SSON, HAN, MIN SOO, KANG, YONG KOO
Format Patent
LanguageEnglish
Korean
Published 11.06.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:PURPOSE: A thiazoline compounds and a T-type calcium channel inhibitor containing the same are provided to treat diseases relating to T-type calcium channel overexpression. CONSTITUTION: A thiazoline compounds have a structure of chemical formula 1. A composition for preventing and treating diseases relating to T-type calcium channel overexpression contains the thiazoline compounds of chemical formula 1. The diseases are Parkinson's disease, Alzheimer, schizophrenia, somnopathy, pain, hypertension, arrhythmia, angina, cardiac insufficiency, myocardial infarction, or cancer.
Bibliography:Application Number: KR20080121802