1,1,1-TRIFLUORO-2-HYDROXY-3-PHENYLPROPANE DERIVATIVES

The present invention relates to compounds of formula (1), wherein A, n, Rto Rand Rto Rare as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as dia...

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Main Authors PETERS JENS UWE, OBST SANDER ULRIKE, HUNZIKER DANIEL, SCHULZ GASCH TANJA, LERNER CHRISTIAN, HERTEL CORNELIA, PFLIEGER PHILIPPE, BAILLY JACQUES
Format Patent
LanguageEnglish
Korean
Published 13.05.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (1), wherein A, n, Rto Rand Rto Rare as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
Bibliography:Application Number: KR20107006692