USE OF A CHROMATOGRAPHY SUBSTRATE FOR REDUCING THE AMOUNT OF ADAMTS13 IN A SOLUTION DERIVED FROM PLASMA

The invention relates to the use of an ion-exchange chromatography substrate including a resin of the large-pore vinylic polymer type including DEAE groups and a buffer including trisodic citrate, sodium chloride, calcium chloride, glycine and lysine for reducing the amount of ADAMTS13 present in a...

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Bibliographic Details
Main Authors SCHMITTHAEUSLER ROLAND, BRIDEY FRANCOISE
Format Patent
LanguageEnglish
Korean
Published 22.04.2010
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:The invention relates to the use of an ion-exchange chromatography substrate including a resin of the large-pore vinylic polymer type including DEAE groups and a buffer including trisodic citrate, sodium chloride, calcium chloride, glycine and lysine for reducing the amount of ADAMTS13 present in a solution derived from plasma containing a human von Willebrand factor.
Bibliography:Application Number: KR20107000053