COMPOSITION FOR INHIBITING SARS CORONAVIRUS COMPRISING ARYL DIKETOACID DERIVATIVES

PURPOSE: A SARS coronavirus helicase and/or composition for suppressing SARS coronavirus helicase containing aryl diketoacid(ADK) are/is provided to suppress DNA double strand unwinding of SARS coronavirus helicase. CONSTITUTION: An inhibitor of DNA double strand unwinding of SARS coronavirus helica...

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Bibliographic Details
Main Authors LEE, CHAE WOON, JEONG, YONG JOO, CHONG, YOU HOON
Format Patent
LanguageEnglish
Korean
Published 17.03.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A SARS coronavirus helicase and/or composition for suppressing SARS coronavirus helicase containing aryl diketoacid(ADK) are/is provided to suppress DNA double strand unwinding of SARS coronavirus helicase. CONSTITUTION: An inhibitor of DNA double strand unwinding of SARS coronavirus helicase contains a compound of chemical formula 1 and its pharmaceutically acceptable salt. In chemical formula 1, R1 is hydrogen, R2-R5 are independently hydrogen, or R6-(CH2)n-R7, R6 is O or NH, n IS 1-3 integer, and R7 is phenyl or one or more halogen-substituted phenyl. A composition for suppressing SARS coronavirus contains the compound of chemical formula 1 and its pharmaceutically acceptable salt as active ingredient. Daily dose for an adult is 1mg to 1000mg once to several times a day. The composition is administered within 24 hours after coronavirus exporsrure.
Bibliography:Application Number: KR20080088348