THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES

It is intended to provide a remedy and a diagnostic for a brain disease typified by cerebral infarction. Namely, a remedy for a mitochondrial dysfunction brain disease characterized by comprising a combination of (A) a δ-aminolevulinic acid represented by the following general formula (1), its deriv...

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Bibliographic Details
Main Authors MASUBUCHI TAKAHIRO, KUROIWA TOSHIHIKO, KAJIMOTO YOSHINAGA, TANAKA TOHRU, ISHIZUKA MASAHIRO
Format Patent
LanguageEnglish
Published 10.02.2010
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:It is intended to provide a remedy and a diagnostic for a brain disease typified by cerebral infarction. Namely, a remedy for a mitochondrial dysfunction brain disease characterized by comprising a combination of (A) a δ-aminolevulinic acid represented by the following general formula (1), its derivative or a salt thereof with (B) an iron compound: RRNCHCOCHCHCOR(1) wherein Rand Rindependently represent each a hydrogen atom or an alkyl, acyl, alkoxycarbonyl, aryl or aralkyl group; and Rrepresents a hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, aryloxy, aralkyloxy or amino group.
Bibliography:Application Number: KR20097020513