USE IN ANTI-CANCER AGENT OF DEOXYPODOPHYLLOTOXIN

PURPOSE: A pharmaceutical composition for suppressing cancer proliferation containing deoxypodophyllotoxin is provided to induce apoptosis and cell cycle arrest. CONSTITUTION: A composition for anti-cancer which induces suppression of cancer cell proliferation and induces apoptosis contains deoxypod...

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Main Authors YONG, YEON JOONG, LIM, YOONG HO, LEE, YOUNG HAN, SHIN, SOON YOUNG
Format Patent
LanguageEnglish
Published 19.11.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A pharmaceutical composition for suppressing cancer proliferation containing deoxypodophyllotoxin is provided to induce apoptosis and cell cycle arrest. CONSTITUTION: A composition for anti-cancer which induces suppression of cancer cell proliferation and induces apoptosis contains deoxypodophyllotoxin of the chemical formula 1 as an active ingredient. The deoxypodophyllotoxin is isolated from Anthriscus sylvestris Hoffm. A method for isolating Anthriscus sylvestris Hoffm. Comprises: a step of isolating from dried Anthriscus sylvestris Hoffm. using solvent; a step of filtering and concentrating Anthriscus sylvestris Hoffm. Extract; and a step of purifying through chromatography. The cancer cell is Hela cell.
Bibliography:Application Number: KR20080044974