PEGYLATED LIPOSOME CONTAINING CROMOLYN AND THE PREPARATION METHOD THEREOF

PURPOSE: A PEGylated liposome containing cromolyn is provided to prevent damage caused by phagocytic cell of RES and enhance retention time. CONSTITUTION: A PEGylated liposome containing cromolyn comprises dipalmitoyl phosphatidylcholine(DPPC), dimyristoyl phosphatidylcholine(DMPC), phospholipid of...

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Bibliographic Details
Main Authors KIM, JIN SEOK, LIM, SUN KYUNG
Format Patent
LanguageEnglish
Korean
Published 04.11.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: A PEGylated liposome containing cromolyn is provided to prevent damage caused by phagocytic cell of RES and enhance retention time. CONSTITUTION: A PEGylated liposome containing cromolyn comprises dipalmitoyl phosphatidylcholine(DPPC), dimyristoyl phosphatidylcholine(DMPC), phospholipid of distearoyl phosphatidylcholine(DSPC), and distearoylphosphatidylethanolamine-methoxypolyethyleneglycol(DSPE-mPEG) in the molar ratio of 4:1:1:0.1~0.3.
Bibliography:Application Number: KR20080040633