COMPOSITE MATERIAL OF SILICIFIED PHOSPHOLIPIDS COATED ON INORGANIC POWDERS FOR PHARMACEUTICALLY ACTIVE OR COSMETICALLY FUNCTIONAL INGREDIENTS AND DRUG DELIVERY SYSTEM USING THE SAME

An inorganic complex powder which is coated with a silica solid lipid layer is provided to continuously contain drug and improve the function of controlled release. A complex contains plate shape inorganic material and silica solid lipid layer. The silica solid lipid layer is coated on the inorganic...

Full description

Saved in:
Bibliographic Details
Main Authors KANG, SANG HWA, CHANG, JEONG HO
Format Patent
LanguageEnglish
Published 09.06.2009
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:An inorganic complex powder which is coated with a silica solid lipid layer is provided to continuously contain drug and improve the function of controlled release. A complex contains plate shape inorganic material and silica solid lipid layer. The silica solid lipid layer is coated on the inorganic material. The silica solid lipid layer is formed through silicification of hydrophilic head domain in phospholipid. The inorganic material is talc or sericite. A method for manufacturing the complex comprises: a step (a) of chelating the organic material with bivalent metal; a step (b) of coating lipid component on the chelated inorganic material; and a step (c) of forming the silicate coating on the lipid-coated organic material. A drug delivery system contains the drug using the complex.
Bibliography:Application Number: KR20070125079