SNP FOR DIAGNOSING SCHIZOPHRENIA, MICROARRAY AND KIT COMPRISING THE SAME

An SNP(single nucleotide polymorphism) is provided to diagnose disease occurrence and its probability of schizophrenia at an early stage and diagnose and treat schizophrenia. A microarray and a kit are also provided to diagnose presence or risk of schizophrenia. An SNP for diagnosis of schizophrenia...

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Bibliographic Details
Main Authors CHOI, JONG SOON, KIM, HAK JAE, JUNG, JOO HO
Format Patent
LanguageEnglish
Published 19.09.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:An SNP(single nucleotide polymorphism) is provided to diagnose disease occurrence and its probability of schizophrenia at an early stage and diagnose and treat schizophrenia. A microarray and a kit are also provided to diagnose presence or risk of schizophrenia. An SNP for diagnosis of schizophrenia comprises a polynucleotide consisting of 8 or more, preferably 8-70 consecutive nucleotides containing a 301st base of rs2765042 polynucleotide of SEQ ID NO:3 in CKB(creatine kinase, brain-specific) gene. A microarray for diagnosis of schizophrenia comprises a polynucleotide consisting of 8 or more consecutive nucleotides, immobilized to a substrate selected from silicon wafer, glass, quartz, metal and plastic, which is coated by an active group selected from amino-silane, poly-L-lysine and aldehyde, a polypeptide encoded thereby or its cDNA(complementary DNA). A kit for diagnosis of schizophrenia contains the microarray.
Bibliography:Application Number: KR20080061864