ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE

The invention relates to a scalable biocatalytic process for the preparation of S-1,1,1-trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast.

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Bibliographic Details
Main Authors HANLON STEVEN PAUL, DOSWALD STEPHAN, KUPFER ERNST
Format Patent
LanguageEnglish
Published 28.02.2008
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a scalable biocatalytic process for the preparation of S-1,1,1-trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1,1,1-trifluoroacetone with Baker's yeast.
Bibliography:Application Number: KR20087000363