OLIGOMER PROBE ARRAY AND METHOD OF FABRICATING THE SAME

• Main Authors: KIM, KYOUNG SEON, CHI, SUNG MIN, RYOO, MAN HYOUNG, HAH, JUNG HWAN, KIM, WON SUN, CHOI, SANG JUN
• Format: Patent
• Language: English
• Published: 27.02.2008
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

An oligomer probe array is provided to improve focusing efficiency at exposure by using near-infrared rays having lower energy intensity than ultraviolet rays as exposure source, and form nano probe cell actives, so that it is useful for the microarray and high integration of oligomer probe array. An oligomer probe array comprises: a substrate; an oligomer probe on the substrate; and an active membrane formed as a polymer containing a monomer having a two-photon absorption group, a monomer having a photo-crosslinking functional group and a monomer having a function group capable of coupling with the oligomer probe directly or indirectly, wherein the photo-crosslinking functional group is cinnamoyl group; and the polymer is represented by the formula in which X is a group represented by the structure of an electron donor or electron acceptor-pi electron center-electron donor or electron acceptor, Y is hydroxyl group, aldehyde group, carboxyl group, amino group, amide group, thiol group, halo group or sulfonate group, R1 is hydrogen or C1-4 alkyl group, R2 is C1-4 alkylene group, C1-4 alkoxy group or phenylene group, R3 is C1-8 alkylene group or C1-8 alkoxy group, R4 is hydrogen or methyl group. Further, the active membrane is separated into a plurality of probe cell actives.