ANTIBODIES AND RELATED MOLECULES THAT BIND TO 161P2F10B PROTEINS

Antibodies and molecules derived therefrom that bind to 161P2F10B protein and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, pro...

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Main Authors JIA XIAO CHI, RAITANO ARTHUR B, KANNER STEVEN B, MORRISON KAREN JANE MEYRICK, GUDAS JEAN, MORRISON ROBERT KENDALL, JAKOBOVITS AYA, SATPAEV DAULET, CHALLITA EID PIA M, PEREZ VILLAR JUAN J
Format Patent
LanguageEnglish
Published 07.01.2008
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Antibodies and molecules derived therefrom that bind to 161P2F10B protein and variants thereof, are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 161P2F10B can be used in active or passive immunization.
Bibliography:Application Number: KR20077025334