MIXED SOLVATE OF OLANZAPINE, METHOD FOR PREPARING IT AND METHOD FOR PREPARING FORM I OF OLANZAPINE THEREFROM
Said mixed solvate is a solvate of olanzapine/water/tetrahydrofuran in the proportion 1:1:1/2 (I). The method for preparing said solvate comprises treating a crude anhydrous olanzapine with a mixture of tetrahydrofuran/water. The method for preparing Form I of olanzapine includes desolvating the mix...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
19.06.2007
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Subjects | |
Online Access | Get full text |
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Summary: | Said mixed solvate is a solvate of olanzapine/water/tetrahydrofuran in the proportion 1:1:1/2 (I). The method for preparing said solvate comprises treating a crude anhydrous olanzapine with a mixture of tetrahydrofuran/water. The method for preparing Form I of olanzapine includes desolvating the mixed solvate of formula I, by means of drying, in vacuo and under temperature-controlled conditions. |
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Bibliography: | Application Number: KR20077002091 |