Microemulsion comprising metabolites of ginseng saponin as effective component and preparation method and skin care compositions for antiaging agent utilizing thereof

• Main Authors: KIM, HAN GON, JU, HUI GYEONG, YOO, BYEONG HUI, KANG, BYEONG YEONG, YUM, MYEONG HUN, SUNG, DAE SEOK, HAN, SANG HUN
• Format: Patent
• Language: English; Korean
• Published: 18.12.2003
• Edition: 7
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

PURPOSE: A cosmetic composition for inhibiting skin aging obtained by allowing emulsion particles and a liposome to contain bio GF 1K using a skin-compatible emulsifier and nanoemulsion techniques is provided. Therefore, it maximizes the transdermal absorption rate and has an excellent effect on the prevention of skin aging such as wrinkles reduction. CONSTITUTION: An anti-aging cosmetic composition contains a metabolite of ginseng as an effective ingredient, an emulsifier, a co-emulsifier and a surfactant. The metabolite of ginseng contains 30 to 50% by weight of a compound K represented by the formula 1, 5 to 25% by weight of ginsenoside F1 represented by the formula 2 and 5 to 25% by weight of 20-o-£α-L-arabinopyranosyl|-20(S)-protopanaxadiol represented by the formula 3 as an active component and has a particle size of 30 to 500nm. In formula, R1 is o-Glc, R2 is OH, R3 is H. The emulsifier contains a liposome containing lecithin or lecithin derivatives. 본 발명은 당 전환반응에 의하여 제조된 인삼의 주요대사산물인 화합물 K(20-O-β-D-글루코피라노실-20(S)-프로토파낙사다이올), 진세노사이드 (Ginsenoside) F1(20-O-β-D-글루코피라노실-20(S)-프로토파낙사트리올) 및 20-O-[α-L-아라비노피라노실(1->6)-β-D-글루코피라노실]-20(S)-프로토파낙사다이올을 주요 유효성분으로 하는 바이오 GF1K(Bio GF1K)를 나노유화기술을 사용하여 미세한 유화입자 및 리포좀 내부에 함유시킴으로써 피부흡수를 극대화한 화장료 조성물에 관한 것으로, 이로 인해 우수한 피부세포 증식 및 콜라겐 생합성 촉진 효과를 얻을 수 있다.