Dip coating compositions containing cellulose ethers

• Main Authors: MCNALLY GERARD P, WIEAND DENNIS C, GULIAN CYNTHIA, MARKLEY THOMAS J, GOWAN WALTER G. JR, MORRIS JOSEPH M, PAREKH KISHOR B
• Format: Patent
• Language: English; Korean
• Published: 22.11.2002
• Edition: 7
• Subjects: BABY COMFORTERS; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR RECEIVING SPITTLE; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

PURPOSE: Provided are gelatin-free compositions for dip coating substrates, such as tablets and capsules, and methods for producing such dosage forms. Also, provided is a method for increasing the weight gain of a water soluble, gelatin-free, film forming coating on a dip-coated tablet or caplet. CONSTITUTION: The water soluble composition for dip-coating a substrate comprises: (a) hydroxypropylmethyl cellulose; and (b) a thickener selected from the group consisting of xanthan gum, carrageenan and mixtures thereof, wherein the composition possesses a surface gloss of at least 150 when applied via dip coating to a substrate. 본 발명은 하이드록시프로필메틸 셀룰로즈(HPMC)와 크산탄 검, 카라게난 및 이들의 혼합물을 포함하거나 HPMC와 피마자유 또는 말토덱스트린을 포함하는, 정제와 같은 약제학적 고체 투여형을 피복시키기 위한, 젤라틴 비함유 수용성 침지 피막에 관한 것이다.