anti pityrosporum ovale IgY and its uses

• Main Authors: JANG, GI HO, JUN, JIN HUI, LEE, JONG HWA, YOO, CHANG SEON, SA, GONG JEONG, JANG, DONG IL
• Format: Patent
• Language: English; Korean
• Published: 19.10.2002
• Edition: 7
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

PURPOSE: An immunoglobulin Y(IgY) antibody for the treatment of seborrhoeic dermatitis and the use thereof are provided, thereby the activity and growth of Pityrosporum ovale can be effectively inhibited, so that seborrhoeic dermatitis can be treated. CONSTITUTION: The immunoglobulin Y(IgY) antibody for the treatment of seborrhoeic dermatitis is prepared by the steps of: culturing Pityrosporum ovale in Brucella broth containing Skirrow's supplement and sterilized oil at 37 deg. C for 3 to 4 days; centrifuging the cultured medium to collect pellet; subjecting the pellet to ultrasonic wave; filtrating the ultrasonic wave treated pellet with multipore cellulose or nylon mesh to obtain water-insoluble cell wall components of Pityrosporum ovale; injecting the filtered cell wall components of Pityrosporum ovale into laying hens; collecting yolk or serum from the laying hens; and freeze-drying or spray-drying the yolk or serum containing IgY antibody. 본 발명은 피티로스포룸 오발레 () 균을 초음파로 처리하여 항원체를 제조하는 방법과 항원체를 산란계에 면역시키고 산란계로부터 생성된 계란의 난황으로부터 분리한 비듬, 지루성 피부염 치료용 신규 난황 IgY 항체를 생산하는 것과 이 난황체를 응용한 비듬치료용,지루성피부개선용 조성물에 관한 것이다.