New propenoic ester and amide compound having oxime side chain process for preparing same and antifungal composition comprising same

• Main Authors: MIN, YONG GI, KIM, GYEONG MAN, KIM, BEOM TAE, PARK, NO GYUN, LEE, YEON SU, KIM, HEUNG TAE
• Format: Patent
• Language: English; Korean
• Published: 30.05.2002
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

PURPOSE: Provided are novel propanoic ester and amide derivatives having an oxime group as a branched chain, which are excellent in disinfecting activity, a preparation thereof, and a disinfectant composition containing the propanoic ester and amide derivatives. CONSTITUTION: The propaonic ester and amide derivatives represented by the formula 1 are produced by a process comprising the steps of: reacting a bromine compound represented by the formula 2 and 2,3-butanedione monoxime represented by the formula 3 in the presence of a base to produce an oxime-based ketone compound; reducing the oxime-based ketone compound or condensing the oxime-based ketone compound with a hydroxyl amine to produce an oxime-based alcohol compound or a dioxime-based compound; reacting the oxime-based alcohol compound or the dioxime-based compound with a propanyl fluoride compound in the presence of a base. In the formula, R1 is trifluoromethyl, R2 is a phenyl group, X is CH or N, and Y is O or NH. 본 발명은 살균 활성이 우수한 다음 화학식 1로 표시되는 옥심기를 측쇄로 하는 신규의 프로페노익 에스테르 및 아미드 유도체, 이의 제조방법 그리고 이를 함유하는 살균제 조성물에 관한 것이다. 상기 화학식 1에서 : R, X 및 Y는 각각 발명의 상세한 설명에서 정의한 바와 같다.