PROCESS FOR TRIFLUOROACETATE ESTERS AND THIOESTERS

PURPOSE: A method for producing trifluoroacetate esters and thioesters is provided, to improve the yield and the purity and to allow the reaction to be carried out at a rather lower temperature. CONSTITUTION: The trifluoroacetate esters are produced by reacting trifluoroacetyl chloride with a compou...

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Bibliographic Details
Main Authors ABDESAKEN FEREVDON, CHONG JOSHUA ANTHONY, SPANGLER LORI ANN
Format Patent
LanguageEnglish
Korean
Published 15.06.2001
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Summary:PURPOSE: A method for producing trifluoroacetate esters and thioesters is provided, to improve the yield and the purity and to allow the reaction to be carried out at a rather lower temperature. CONSTITUTION: The trifluoroacetate esters are produced by reacting trifluoroacetyl chloride with a compound represented by RXH in the initial presence of a trifluoroacetate compound of the formula(I) at a temperature below 20 deg.C, to obtain a trifluoroacetate compound of the formula(I); and degassing the mixture at a room temperature to remove the by-product HCl and the remaining triacetyl chloride, wherein R is an alkyl group, an alkoxy group or an alkyl group substituted with a haloalkoxy group, and X is O or S. The RXH is preferably ethanol or ethanethiol. The molar ratio C/B is preferably 1.10 : 0.90. 본 발명은 에스테르 또는 티오에스테르가 용매로서 존재하면서 트리플루오로아세틸 클로라이드와 알콜 또는 티올로부터 트리플루오로아세트산의 에스테르류 또는 티오에스테르류를 제조하기 위한 방법을 제공한다. 트리플루오로아세트산의 에스테르류 및 티오에스테르류는 의약품, 농약품, 액정, 염료 및 산업용 화학물질들을 제조하는데 사용될 수 있는, 정밀화학 중간체이다. 트리플루오로아세테이트 및 티오에스테르류는 또한 다른 정밀 화학 물질, 의약품, 농약, 액정 산업용 화학물질 및 염료를 제조하는데 용매로서 사용될 수 있다.
Bibliography:Application Number: KR20000041680