PROCESS FOR PRODUCING DROSPIRENONE (6BETA,7BETA;15BETA,16BETA-DIMETHYLENE-3-OXO-17 ALPHA -PREGN-4-EN-21,17-CARBOLACTONE, DRSP), AS WELL AS 7 A

PURPOSE: Provided is a process for producing drospirenone (6beta,7beta; 15beta,16beta-dimethylene-3-oxo-17 alpha-pregn-4-en-21,17-carbolate, drsp), as well as 7a CONSTITUTION: Provided is a process for producing drospirenone (6 beta,7 beta; 15 beta,16 beta -dimethylene-3-oxo-17 alpha -pregn-4-en-21,...

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Bibliographic Details
Main Authors NICKISCH KLAUS, MOHR JOERG-TORSTEN
Format Patent
LanguageEnglish
Published 25.05.2000
Edition7
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:PURPOSE: Provided is a process for producing drospirenone (6beta,7beta; 15beta,16beta-dimethylene-3-oxo-17 alpha-pregn-4-en-21,17-carbolate, drsp), as well as 7a CONSTITUTION: Provided is a process for producing drospirenone (6 beta,7 beta; 15 beta,16 beta -dimethylene-3-oxo-17 alpha -pregn-4-en-21,17-carbolate, DRSP) (I) and 7 alpha -(3-hydroxy-1-propyl-6 beta,7 beta; 15 beta,16 beta -dimethylene-5 beta -androstane-3 beta,5,17 beta -triol (ZK 92836) and 6 beta,7 beta; 15 beta,16 beta -dimethylene-5 beta -hydroxy-3-oxo-17 alpha -androstane-21,17-carbolate (ZK 90965) used as intermediates in the process.
Bibliography:Application Number: KR19997001166