GENERATING REPLICATING MOLECULES IN VIVO

PURPOSE: A circular replicate DNA molecule being useful for a gene therapy and an effective method for generating the molecule from a virus vector are provided. CONSTITUTION: The invention discloses circular and replicating DNA molecules, useful in gene therapy, as well as a particularly efficient m...

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Bibliographic Details
Main Authors PERRICAUDET, MICHEL, YEH, PATRICE, LEBLOIS-FREHAUD, HELLENE
Format Patent
LanguageEnglish
Korean
Published 25.03.2000
Edition7
Subjects
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Summary:PURPOSE: A circular replicate DNA molecule being useful for a gene therapy and an effective method for generating the molecule from a virus vector are provided. CONSTITUTION: The invention discloses circular and replicating DNA molecules, useful in gene therapy, as well as a particularly efficient method for generating them in situ from a viral vector. Herein, the viral vector is surrounded by two sequences being located toward a direct orientation and includes the DNA area including at least one reproduction origin and one corresponding gene. 본 발명은 유전자 요법에 유용한 환상의 복제성 DNA 분자, 및 이를 바이러스 벡터로부터 그 자리에서 생성시키기에 특히 효율적인 방법에 대하여 개시한다.
Bibliography:Application Number: KR19980710112